15 Night Panama Canal Eastward Cruise

15 nights · 7 Oct 2027 – 22 Oct 2027 · aboard Serenade of the Seas

Americas South America Panama Canal Family Friendly
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£1,410 pp
15 nights · Serenade of the Seas

Route map

15 nights 7 ports 6 countries ~4,015 nautical miles

Approximate route shown as straight lines between ports. Actual sailing path may vary. Map data © OpenStreetMap contributors.

Itinerary

Departs San Diego, California, United States · 15 nights · ends Tampa, Florida, United States · Americas

  1. San Diego, California
    Thu 7 Oct · Day 1

    San Diego, California United States

    Dep 17:00
    San Diego is a vacationer's paradise, with year-round temperatures in the seventies and near-constant sunshine. One of America's most family-friendly cities, San Diego is home to LEGOLAND, the New Children's Museum, and the famous San Diego…
    Port guide →
  2. Fri 8 Oct Day 2
    At sea · A day to enjoy the ship
  3. Sat 9 Oct Day 3
    At sea · A day to enjoy the ship
  4. Puerto Vallarta
    Sun 10 Oct · Day 4

    Puerto Vallarta Mexico

    Arr 08:00 · Dep 17:00
    Puerto Vallarta is a resort town on Mexico’s Pacific coast, in Jalisco state. It is known for its beaches, water sports and nightlife scene. Its cobblestone center is home to the ornate Nuestra Señora de Guadalupe church, boutique shops and…
    Port guide →
  5. Mon 11 Oct Day 5
    At sea · A day to enjoy the ship
  6. Tue 12 Oct Day 6
    At sea · A day to enjoy the ship
  7. Puerto Quetzal
    Wed 13 Oct · Day 7

    Puerto Quetzal Guatemala

    Arr 08:00 · Dep 17:00
    Puerto Quetzal is Guatemala's largest Pacific Ocean port. It is important for both cargo traffic and as a stop-off point for cruise liners
    Port guide →
  8. Thu 14 Oct Day 8
    At sea · A day to enjoy the ship
  9. Puntarenas
    Fri 15 Oct · Day 9

    Puntarenas Costa Rica

    Arr 08:00 · Dep 17:00
    This town is not on the Nicoya Peninsula, but rather on Costa Rica's mainland. It is best known as a cruise-ship port and launching pad for ferries heading southeast to the coast of the Nicoya Peninsula and for cruises sailing out on the…
    Port guide →
  10. Sat 16 Oct Day 10
    At sea · A day to enjoy the ship
  11. Sun 17 Oct · Day 11

    Panama Canal Transit

    Arr 06:00 · Dep 18:00
  12. Cartagena
    Mon 18 Oct · Day 12

    Cartagena Colombia

    Arr 11:30 · Dep 19:00
    Cartagena's magnificent city walls and fortresses, now a UNESCO World Heritage Site, enclose a well-restored historic center (the Cuidad Amurallada, or walled city) with plazas, churches, museums, and shops that have made it a lively…
    Port guide →
  13. Tue 19 Oct Day 13
    At sea · A day to enjoy the ship
  14. Georgetown, Grand Cayman
    Wed 20 Oct · Day 14

    Georgetown, Grand Cayman Cayman Islands

    Arr 07:00 · Dep 16:00
    Begin exploring the capital by strolling along the waterfront Harbour Drive to Elmslie Memorial United Church, named after the first Presbyterian missionary to serve in Cayman. Its vaulted ceiling, wooden arches, and sedate nave reflect the…
    Port guide →
  15. Thu 21 Oct Day 15
    At sea · A day to enjoy the ship
  16. Tampa, Florida
    Fri 22 Oct · Day 16

    Tampa, Florida United States

    Arr 05:00
    Home to a large number of museums, and often considered one of the best destinations for the arts in the US, Tampa is a must see for anyone interested in the arts, contemporary or older. The Museum of Science and Industry is also an…
    Port guide →

Cabin grades & pricing

Prices are per person and based on the lowest available cabin within each grade. Confirm the final price with the cruise line at booking.

Savings NRD IA641522

Cabin grade Double pp Single pp Availability
Ocean View Balcony Guarantee (XB)
balcony
£2,505 available
Ocean View Balcony (4D)
balcony
£2,784 available
Ocean View Balcony (3D)
balcony
£2,821 available
Ocean View Balcony (1D)
balcony
£2,835 available
Connecting Balcony (CB)
balcony
£2,930 £4,379 available
Spacious Ocean View Balcony (2B)
balcony
£2,982 £4,457 available
Spacious Ocean View Balcony (3B)
balcony
£2,990 £4,469 available
Spacious Ocean View Balcony (1B)
balcony
£2,996 £4,478 available

Taxes & fees: £368 per person (typical).

Savings NRD IA641521

Cabin grade Double pp Single pp Availability
Interior Guarantee (ZI)
inside
£1,327 available
Interior (4V)
inside
£1,436 £2,093 available
Interior (2V)
inside
£1,473 £2,148 available
Interior (5V)
inside
£1,495 £2,181 available
Interior (3V)
inside
£1,510 available
Interior (1V)
inside
£1,539 available
Studio Interior (2W)
inside
£2,553 available
Ocean View Guarantee (YO)
outside
£1,583 available
Ocean View (4N)
outside
£1,693 £2,478 available
Ocean View (2N)
outside
£1,708 £2,501 available
Ocean View (5N)
outside
£1,730 available
Ocean View (3N)
outside
£1,752 available
Ocean View (1N)
outside
£1,761 available
Connecting Oceanview (CO)
outside
£1,768 £2,591 available
Spacious Ocean View (4M)
outside
£1,965 £2,886 available
Ultra Spacious Ocean View (1K)
outside
£2,854 £4,220 available

Taxes & fees: £368 per person (typical).

Shore excursions on this cruise

A small selection of trusted tours at the ports this cruise visits. Browse the full list per port from the itinerary above, or visit all excursions.

About this cruise

Departing San Diego, California, United States, on 7 October 2027, Serenade of the Seas operates this 15-night Royal Caribbean International sailing. Rather than returning to San Diego, California, this itinerary ends at Tampa, Florida, United States. The itinerary covers destinations in the Americas. The ship carries a Resort rating, which gives a broad indication of the onboard experience. See the route map, day-by-day itinerary, and cabin pricing on this page.

This summary is drawn from the operator's sailing data. We update these pages as more detail becomes available.

Frequently asked questions

What's included depends on the fare type you select. Accommodation and meals in the main dining room are standard on most sailings; speciality restaurants, drinks, and gratuities are typically paid extras. Check directly with Royal Caribbean International for the current fare breakdown.

Reservations for this sailing are made directly with Royal Caribbean International. CruiseCompass does not process bookings — visit Royal Caribbean International's website to check availability.

The cancellation policy for this sailing is determined by Royal Caribbean International and may vary depending on your chosen fare. Most operators apply a sliding scale of charges that increases closer to departure, with deposits often non-refundable once paid. Always check the full booking conditions with Royal Caribbean International before confirming.